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Dokumenttyp:
journal article 
Autor(en):
Hotze, M; Baurecht, H; Rodríguez, E; Chapman-Rothe, N; Ollert, M; Fölster-Holst, R; Adamski, J; Illig, T; Ring, J; Weidinger, S 
Titel:
Increased efficacy of omalizumab in atopic dermatitis patients with wild-type filaggrin status and higher serum levels of phosphatidylcholines. 
Abstract:
Omalizumab, a monoclonal antibody targeting IgE, is an established therapy for severe allergic asthma and has shown efficacy in chronic spontaneous urticaria. Small-scale studies indicated some beneficial effect also in atopic dermatitis (AD). To evaluate the efficacy of omalizumab in AD and to identify markers associated with treatment response, we conducted a prospective 28-week open-label trial on 20 adults with moderate-to-severe AD. Our results confirm previous observations of a positive re...    »
 
Zeitschriftentitel:
Allergy 
Jahr:
2014 
Band / Volume:
69 
Heft / Issue:
Seitenangaben Beitrag:
132-5 
Sprache:
eng 
Print-ISSN:
0105-4538 
TUM Einrichtung:
Institut für Molekulare Allergologie und Umweltforschung; Klinik und Poliklinik für Dermatologie und Allergologie