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Dokumenttyp:
journal article 
Autor(en):
Vong, Queenie P; Leung, Wai-Hang; Houston, Jim; Li, Ying; Rooney, Barbara; Holladay, Martha; Oostendorp, Robert A J; Leung, Wing 
Titel:
TOX2 regulates human natural killer cell development by controlling T-BET expression. 
Abstract:
Thymocyte selection-associated high mobility group box protein family member 2 (TOX2) is a transcription factor belonging to the TOX family that shares a highly conserved high mobility group DNA-binding domain with the other TOX members. Although TOX1 has been shown to be an essential regulator of T-cell and natural killer (NK) cell differentiation in mice, little is known about the roles of the other TOX family members in lymphocyte development, particularly in humans. In this study, we found t...    »
 
Zeitschriftentitel:
Blood 
Jahr:
2014 
Band / Volume:
124 
Heft / Issue:
26 
Seitenangaben Beitrag:
3905-13 
Sprache:
eng 
Print-ISSN:
0006-4971 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik