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Dokumenttyp:
journal article 
Autor(en):
Tassara, Michela; Döhner, Konstanze; Brossart, Peter; Held, Gerhard; Götze, Katharina; Horst, Heinz-A; Ringhoffer, Mark; Köhne, Claus-Henning; Kremers, Stephan; Raghavachar, Aruna; Wulf, Gerald; Kirchen, Heinz; Nachbaur, David; Derigs, Hans Günter; Wattad, Mohammed; Koller, Elisabeth; Brugger, Wolfram; Matzdorff, Axel; Greil, Richard; Heil, Gerhard; Paschka, Peter; Gaidzik, Verena I; Göttlicher, Martin; Döhner, Hartmut; Schlenk, Richard F 
Titel:
Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients. 
Abstract:
The outcome of patients with acute myeloid leukemia who are older than 60 years has remained poor because of unfavorable disease characteristics and patient-related factors. The randomized German-Austrian AML Study Group 06-04 protocol was designed on the basis of in vitro synergistic effects of valproic acid (VPA) and all-trans retinoic acid with chemotherapy. Between 2004 and 2006, 186 patients were randomly assigned to receive 2 induction cycles with idarubicin, cytarabine, and all-trans reti...    »
 
Zeitschriftentitel:
Blood 
Jahr:
2014 
Band / Volume:
123 
Heft / Issue:
26 
Seitenangaben Beitrag:
4027-36 
Sprache:
eng 
Print-ISSN:
0006-4971 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik