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Document type:
journal article 
Author(s):
Bakchoul, T; Assfalg, V; Zöllner, H; Evert, M; Novotny, A; Matevossian, E; Friess, H; Hartmann, D; Hron, G; Althaus, K; Greinacher, A; Hüser, N 
Title:
Anti-platelet factor 4/heparin antibodies in patients with impaired graft function after liver transplantation. 
Abstract:
Heparin, the standard perioperative anticoagulant for the prevention of graft vessel thrombosis in patients undergoing liver transplantation (LT), binds to the chemokine platelet factor 4 (PF4). Antibodies that are formed against the resulting PF4/heparin complexes can induce heparin-induced thrombocytopenia. LT is a clinical situation that allows the study of T-cell dependency of immune responses because T-cell function is largely suppressed pharmacologically in these patients to prevent graft...    »
 
Journal title abbreviation:
J Thromb Haemost 
Year:
2014 
Journal volume:
12 
Journal issue:
Pages contribution:
871-8 
Language:
eng 
Print-ISSN:
1538-7933 
TUM Institution:
Chirurgiesche Klinik und Poliklinik