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Document type:
journal article 
Author(s):
Baliu-Piqué, Mariona; Jusek, Gabriela; Holzmann, Bernhard 
Title:
Neuroimmunological communication via CGRP promotes the development of a regulatory phenotype in TLR4-stimulated macrophages. 
Abstract:
Environmental signals shape the phenotype and function of activated macrophages. Here, we show that the neuropeptide calcitonin gene-related peptide (CGRP), which is released from sensory nerves, modulates the phenotype of TLR4-activated murine macrophages by enhancing expression of the regulatory macrophage markers IL-10, sphingosine kinase 1 (SPHK1), and LIGHT (lymphotoxin-like, exhibits inducible expression and competes with HSV glycoprotein D for herpesvirus entry mediator, a receptor expres...    »
 
Journal title abbreviation:
Eur J Immunol 
Year:
2014 
Journal volume:
44 
Journal issue:
12 
Pages contribution:
3708-16 
Language:
eng 
Print-ISSN:
0014-2980 
TUM Institution:
Chirurgiesche Klinik und Poliklinik