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Document type:
journal article 
Author(s):
Demir, Ihsan Ekin; Boldis, Alexandra; Pfitzinger, Paulo L; Teller, Steffen; Brunner, Eva; Klose, Natascha; Kehl, Timo; Maak, Matthias; Lesina, Marina; Laschinger, Melanie; Janssen, Klaus-Peter; Algül, Hana; Friess, Helmut; Ceyhan, Güralp O 
Title:
Investigation of Schwann cells at neoplastic cell sites before the onset of cancer invasion. 
Abstract:
In neural invasion (NI), cancer cells are classically assumed to actively invade nerves and to cause local recurrence and pain. However, the opposite possibility, that nerves may reach cancer cells even in their preinvasive stage and thereby promote cancer spread, has not yet been genuinely considered. The present study analyzes the reaction of Schwann cells of peripheral nerves to carcinogenesis in pancreatic cancer and colon cancer.Two novel 3D migration and Schwann cell outgrowth assays were...    »
 
Journal title abbreviation:
J Natl Cancer Inst 
Year:
2014 
Journal volume:
106 
Journal issue:
Language:
eng 
Print-ISSN:
0027-8874 
TUM Institution:
Chirurgiesche Klinik und Poliklinik; II. Medizinische Klinik und Poliklinik