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Dokumenttyp:
journal article 
Autor(en):
Demir, Ihsan Ekin; Boldis, Alexandra; Pfitzinger, Paulo L; Teller, Steffen; Brunner, Eva; Klose, Natascha; Kehl, Timo; Maak, Matthias; Lesina, Marina; Laschinger, Melanie; Janssen, Klaus-Peter; Algül, Hana; Friess, Helmut; Ceyhan, Güralp O 
Titel:
Investigation of Schwann cells at neoplastic cell sites before the onset of cancer invasion. 
Abstract:
In neural invasion (NI), cancer cells are classically assumed to actively invade nerves and to cause local recurrence and pain. However, the opposite possibility, that nerves may reach cancer cells even in their preinvasive stage and thereby promote cancer spread, has not yet been genuinely considered. The present study analyzes the reaction of Schwann cells of peripheral nerves to carcinogenesis in pancreatic cancer and colon cancer.Two novel 3D migration and Schwann cell outgrowth assays were...    »
 
Zeitschriftentitel:
J Natl Cancer Inst 
Jahr:
2014 
Band / Volume:
106 
Heft / Issue:
Sprache:
eng 
Print-ISSN:
0027-8874 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik; II. Medizinische Klinik und Poliklinik