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Dokumenttyp:
journal article 
Autor(en):
Rudolf, Ronald, R; Busch, Rhoda, R; Patra, Amiya K, AK; Muhammad, Khalid, K; Avots, Andris, A; Andrau, Jean-Christophe, JC; Klein-Hessling, Stefan, S; Serfling, Edgar, E 
Titel:
Architecture and expression of the nfatc1 gene in lymphocytes. 
Abstract:
In lymphocytes, the three NFAT factors NFATc1 (also designated as NFAT2), NFATc2 (NFAT1), and NFATc3 (NFAT4 or NFATx) are expressed and are the targets of immune receptor signals, which lead to a rapid rise of intracellular Ca(++), the activation of phosphatase calcineurin, and to the activation of cytosolic NFATc proteins. In addition to rapid activation of NFAT factors, immune receptor signals lead to accumulation of the short NFATc1/?A isoform in lymphocytes which controls their proliferation...    »
 
Zeitschriftentitel:
Front Immunol 
Jahr:
2014 
Band / Volume:
Seitenangaben Beitrag:
21 
Sprache:
eng 
TUM Einrichtung:
r Medizinische Statistik und Epidemiologie