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Document type:
journal article 
Author(s):
Gaipl, Udo S; Multhoff, Gabriele; Scheithauer, Heike; Lauber, Kirsten; Hehlgans, Stefanie; Frey, Benjamin; Rödel, Franz 
Title:
Kill and spread the word: stimulation of antitumor immune responses in the context of radiotherapy. 
Abstract:
Besides the direct, targeted effects of ionizing irradiation (x-ray) on cancer cells, namely DNA damage and cell death induction, indirect, nontargeted ones exist, which are mediated in large part by the immune system. Immunogenic forms of tumor cell death induced by x-ray, including immune modulating danger signals like the heat shock protein 70, adenosine triphosphate, and high-mobility group box 1 protein are presented. Further, antitumor effects exerted by cells of the innate (natural killer...    »
 
Journal title abbreviation:
Immunotherapy 
Year:
2014 
Journal volume:
Journal issue:
Pages contribution:
597-610 
Language:
eng 
Print-ISSN:
1750-743X 
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie