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Dokumenttyp:
journal article 
Autor(en):
Gaipl, Udo S; Multhoff, Gabriele; Scheithauer, Heike; Lauber, Kirsten; Hehlgans, Stefanie; Frey, Benjamin; Rödel, Franz 
Titel:
Kill and spread the word: stimulation of antitumor immune responses in the context of radiotherapy. 
Abstract:
Besides the direct, targeted effects of ionizing irradiation (x-ray) on cancer cells, namely DNA damage and cell death induction, indirect, nontargeted ones exist, which are mediated in large part by the immune system. Immunogenic forms of tumor cell death induced by x-ray, including immune modulating danger signals like the heat shock protein 70, adenosine triphosphate, and high-mobility group box 1 protein are presented. Further, antitumor effects exerted by cells of the innate (natural killer...    »
 
Zeitschriftentitel:
Immunotherapy 
Jahr:
2014 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
597-610 
Sprache:
eng 
Print-ISSN:
1750-743X 
TUM Einrichtung:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie