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Document type:
journal article 
Gehrmann, Mathias; Specht, Hanno M; Bayer, Christine; Brandstetter, Markus; Chizzali, Barbara; Duma, Marciana; Breuninger, Stephanie; Hube, Kathrin; Lehnerer, Sophie; van Phi, Valerie; Sage, Eva; Schmid, Thomas E; Sedelmayr, Michael; Schilling, Daniela; Sievert, Wolfgang; Stangl, Stefan; Multhoff, Gabriele 
Hsp70--a biomarker for tumor detection and monitoring of outcome of radiation therapy in patients with squamous cell carcinoma of the head and neck. 
Tumor but not normal cells frequently overexpress heat shock protein 70 (Hsp70) and present it on their cell surface (mHsp70) from where it can be actively released. Therefore, membrane (mHsp70) and soluble Hsp70 (sHsp70) were investigated as potential tumor biomarkers and for monitoring the outcome of radiation therapy.Biopsies and blood were collected from patients with squamous cell carcinoma of the head and neck (SCCHN) at different time points (before, during therapy and in the follow-up pe...    »
Journal title abbreviation:
Radiat Oncol 
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TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie; Hals-, Nasen-, Ohrenklinik und Poliklinik