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Document type:
journal article 
Author(s):
Gehrmann, Mathias; Specht, Hanno M; Bayer, Christine; Brandstetter, Markus; Chizzali, Barbara; Duma, Marciana; Breuninger, Stephanie; Hube, Kathrin; Lehnerer, Sophie; van Phi, Valerie; Sage, Eva; Schmid, Thomas E; Sedelmayr, Michael; Schilling, Daniela; Sievert, Wolfgang; Stangl, Stefan; Multhoff, Gabriele 
Title:
Hsp70--a biomarker for tumor detection and monitoring of outcome of radiation therapy in patients with squamous cell carcinoma of the head and neck. 
Abstract:
Tumor but not normal cells frequently overexpress heat shock protein 70 (Hsp70) and present it on their cell surface (mHsp70) from where it can be actively released. Therefore, membrane (mHsp70) and soluble Hsp70 (sHsp70) were investigated as potential tumor biomarkers and for monitoring the outcome of radiation therapy.Biopsies and blood were collected from patients with squamous cell carcinoma of the head and neck (SCCHN) at different time points (before, during therapy and in the follow-up pe...    »
 
Journal title abbreviation:
Radiat Oncol 
Year:
2014 
Journal volume:
Pages contribution:
131 
Language:
eng 
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie; Hals-, Nasen-, Ohrenklinik und Poliklinik