Kuhn, Laura B;Valentin, Stefanie;Stojanovic, Kristina;Strobl, Daniel C;Babushku, Tea;Wang, Yan;Rambold, Ursula;Scheffler, Laura;Grath, Sonja;John-Robbert, Dorothy;Blum, Helmut;Feuchtinger, Annette;Blutke, Andreas;Weih, Falk;Kitamura, Daisuke;Rad, Roland;Strobl, Lothar J;Zimber-Strobl, Ursula
RelB contributes to the survival, migration and lymphomagenesis of B cells with constitutively active CD40 signaling.
Front Immunol
2022
13

Mahajan, Ujjwal M;Oehrle, Bettina;Sirtl, Simon;Alnatsha, Ahmed;Goni, Elisabetta;Regel, Ivonne;Beyer, Georg;Vornhülz, Marlies;Vielhauer, Jakob;Chromik, Ansgar;Bahra, Markus;Klein, Fritz;Uhl, Waldemar;Fahlbusch, Tim;Distler, Marius;Weitz, Jürgen;Grützmann, Robert;Pilarsky, Christian;Weiss, Frank Ulrich;Adam, M Gordian;Neoptolemos, John P;Kalthoff, Holger;Rad, Roland;Christiansen, Nicole;Bethan, Bianca;Kamlage, Beate;Lerch, Markus M;Mayerle, Julia
Independent Validation and Assay Standardization of Improved Metabolic Biomarker Signature to Differentiate Pancreatic Ductal Adenocarcinoma From Chronic Pancreatitis.
Gastroenterology
2022
163
5
1407-1422

Haimovici, Aladin;Höfer, Christoph;Badr, Mohamed Tarek;Bavafaye Haghighi, Elham;Amer, Tarek;Boerries, Melanie;Bronsert, Peter;Glavynskyi, Ievgen;Fanfone, Deborah;Ichim, Gabriel;Thilmany, Nico;Weber, Arnim;Brummer, Tilman;Spohr, Corinna;Öllinger, Rupert;Janssen, Klaus-Peter;Rad, Roland;Häcker, Georg
Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse.
Cell Death Dis
2022
13
4

Kotsiliti, Elena;Leone, Valentina;Schuehle, Svenja;Govaere, Olivier;Li, Hai;Wolf, Monika J;Horvatic, Helena;Bierwirth, Sandra;Hundertmark, Jana;Inverso, Donato;Zizmare, Laimdota;Sarusi-Portuguez, Avital;Gupta, Revant;O'Connor, Tracy;Giannou, Anastasios D;Shiri, Ahmad Mustafa;Schlesinger, Yehuda;Beccaria, Maria Garcia;Rennert, Charlotte;Pfister, Dominik;Öllinger, Rupert;Gadjalova, Iana;Ramadori, Pierluigi;Rahbari, Mohammad;Rahbari, Nuh;Healy, Marc;Fernández-Vaquero, Mirian;Yahoo, Neda;Janzen, Jakob;Singh, Indrabahadur;Fan, Chaofan;Liu, Xinyuan;Rau, Monika;Feuchtenberger, Martin;Schwaneck, Eva;Wallace, Sebastian J;Cockell, Simon;Wilson-Kanamori, John;Ramachandran, Prakash;Kho, Celia;Kendall, Timothy J;Leblond, Anne-Laure;Keppler, Selina J;Bielecki, Piotr;Steiger, Katja;Hofmann, Maike;Rippe, Karsten;Zitzlesberger, Horst;Weber, Achim;Malek, Nisar;Lüdde, Tom;Vucur, Mihael;Augustin, Hellmut G;Flavell, Richard;Parnas, Oren;Rad, Roland;Pabst, Olivier;Henderson, Neil C;Huber, Samuel;Macpherson, Andrew;Knolle, Percy;Claasen, Manfred;Geier, Andreas;Trautwein, Christoph;Unger, Kristian;Elinav, Eran;Waisman, Ari;Abdullah, Zeinab;Haller, Dirk;Tacke, Frank;Anstee, Quentin M;Heikenwalder, Mathias
Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling.
J Hepatol
2023
79
2
296-313

Bayerl, Felix;Meiser, Philippa;Donakonda, Sainitin;Hirschberger, Anna;Lacher, Sebastian B;Pedde, Anna-Marie;Hermann, Chris D;Elewaut, Anais;Knolle, Moritz;Ramsauer, Lukas;Rudolph, Thomas J;Grassmann, Simon;Öllinger, Rupert;Kirchhammer, Nicole;Trefny, Marcel;Anton, Martina;Wohlleber, Dirk;Höchst, Bastian;Zaremba, Anne;Krüger, Achim;Rad, Roland;Obenauf, Anna C;Schadendorf, Dirk;Zippelius, Alfred;Buchholz, Veit R;Schraml, Barbara U;Böttcher, Jan P
Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses.
Immunity
2023
56
6
1341-1358.e11

Bredthauer, Carl;Fischer, Anja;Ahari, Ata Jadid;Cao, Xueqi;Weber, Julia;Rad, Lena;Rad, Roland;Wachutka, Leonhard;Gagneur, Julien
Transmicron: accurate prediction of insertion probabilities improves detection of cancer driver genes from transposon mutagenesis screens.
Nucleic Acids Res
2023
51
4

Götz, Viktoria;Qiao, Sen;Das, Debajyoti;Wartenberg, Philipp;Wyatt, Amanda;Wahl, Vanessa;Gamayun, Igor;Alasmi, Samer;Fecher-Trost, Claudia;Meyer, Markus R;Rad, Roland;Kaltenbacher, Thorsten;Kattler, Kathrin;Lipp, Peter;Becherer, Ute;Mollard, Patrice;Candlish, Michael;Boehm, Ulrich
Ovulation is triggered by a cyclical modulation of gonadotropes into a hyperexcitable state.
Cell Rep
2023
42
6

Paul, Mariel C;Schneeweis, Christian;Falcomatà, Chiara;Shan, Chuan;Rossmeisl, Daniel;Koutsouli, Stella;Klement, Christine;Zukowska, Magdalena;Widholz, Sebastian A;Jesinghaus, Moritz;Heuermann, Konstanze K;Engleitner, Thomas;Seidler, Barbara;Sleiman, Katia;Steiger, Katja;Tschurtschenthaler, Markus;Walter, Benjamin;Weidemann, Sören A;Pietsch, Regina;Schnieke, Angelika;Schmid, Roland M;Robles, Maria S;Andrieux, Geoffroy;Boerries, Melanie;Rad, Roland;Schneider, Günter;Saur, Dieter
Non-canonical functions of SNAIL drive context-specific cancer progression.
Nat Commun
2023
14
1

Fischer, Anja;Lersch, Robert;de Andrade Krätzig, Niklas;Strong, Alexander;Friedrich, Mathias J;Weber, Julia;Engleitner, Thomas;Öllinger, Rupert;Yen, Hsi-Yu;Kohlhofer, Ursula;Gonzalez-Menendez, Irene;Sailer, David;Kogan, Liz;Lahnalampi, Mari;Laukkanen, Saara;Kaltenbacher, Thorsten;Klement, Christine;Rezaei, Majdaddin;Ammon, Tim;Montero, Juan J;Schneider, Günter;Mayerle, Julia;Heikenwälder, Mathias;Schmidt-Supprian, Marc;Quintanilla-Martinez, Leticia;Steiger, Katja;Liu, Pentao;Cadiñanos, Juan;Vassiliou, George S;Saur, Dieter;Lohi, Olli;Heinäniemi, Merja;Conte, Nathalie;Bradley, Allan;Rad, Lena;Rad, Roland
In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution.
Cell Genom
2023
3
3

Donne, Romain;Saroul-Ainama, Maëva;Cordier, Pierre;Hammoutene, Adel;Kabore, Christelle;Stadler, Mira;Nemazanyy, Ivan;Galy-Fauroux, Isabelle;Herrag, Mounia;Riedl, Tobias;Chansel-Da Cruz, Marie;Caruso, Stefano;Bonnafous, Stéphanie;Öllinger, Rupert;Rad, Roland;Unger, Kristian;Tran, Albert;Couty, Jean-Pierre;Gual, Philippe;Paradis, Valérie;Celton-Morizur, Séverine;Heikenwalder, Mathias;Revy, Patrick;Desdouets, Chantal
Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD.
Dev Cell
2022
57
14
1728-1741.e6