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Document type:
Zeitschriftenaufsatz 
Author(s):
Arends, Fabienna; Nowald, Constantin; Pflieger, Kerstin; Boettcher, Kathrin; Zahler, Stefan; Lieleg, Oliver 
Title:
The Biophysical Properties of Basal Lamina Gels Depend on the Biochemical Composition of the Gel 
Abstract:
The migration of cells within a three-dimensional extracellular matrix (ECM) depends sensitively on the biochemical and biophysical properties of the matrix. An example for a biological ECM is given by reconstituted basal lamina gels purified from the Engelbreth-Holm-Swarm sarcoma of mice. Here, we compare four different commercial variants of this ECM, which have all been purified according to the same protocol. Nevertheless, in those gels, we detect strong differences in the migration behavior...    »
 
Keywords:
migration of cells, extracellular matrix, basal lamina gels, Engelbreth-Holm-Swarm 
Dewey Decimal Classification:
610 Medizin und Gesundheit 
Journal title:
PLoS ONE 
Year:
2015 
Journal volume:
10 
Pages contribution:
e0118090 
Covered by:
Web of Science 
Language:
en 
Publisher:
Public Library of Science (PLoS) 
E-ISSN:
1932-6203 
Status:
Verlagsversion / published 
Accepted:
05.01.2015 
Date of publication:
17.02.2015 
Semester:
WS 14-15 
TUM Institution:
Fachgebiet für Biomechanik, MW