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Dokumenttyp:
journal article 
Autor(en):
Schindler, Maria, M; Pendzialek, Mareike, M; Navarrete Santos, Alexander, A; Plösch, Torsten, T; Seyring, Stefanie, S; Gürke, Jacqueline, J; Haucke, Elisa, E; Knelangen, Julia Miriam, JM; Fischer, Bernd, B; Santos, Anne Navarrete, AN 
Titel:
Maternal diabetes leads to unphysiological high lipid accumulation in rabbit preimplantation embryos. 
Abstract:
According to the "developmental origin of health and disease" hypothesis, the metabolic set points of glucose and lipid metabolism are determined prenatally. In the case of a diabetic pregnancy, the embryo is exposed to higher glucose and lipid concentrations as early as during preimplantation development. We used the rabbit to study the effect of maternal diabetes type 1 on lipid accumulation and expression of lipogenic markers in preimplantation blastocysts. Accompanied by elevated triglycerid...    »
 
Zeitschriftentitel:
Endocrinology 
Jahr:
2014 
Band / Volume:
155 
Heft / Issue:
Seitenangaben Beitrag:
1498-509 
Sprache:
eng 
Print-ISSN:
0013-7227 
TUM Einrichtung:
r Virologie