Autor(en):
Klare, P.; Meining, A.; von Delius, S.; Wolf, P.; Konukiewitz, B.; Schmid, R.M.; Bajbouj, M.
Titel:
Argon Plasma Coagulation of Gastric Inlet Patches for the Treatment of Globus Sensation: It Is an Effective Therapy in the Long Term
Abstract:
Aim: To determine the long-term effect of argon plasma coagulation (APC) of gastric inlet patches in the cervical esophagus for patients suffering from globus sensation. Methods: We intended to follow up all patients between 2004 and 2011 (n = 49) who received argon plasma ablation of gastric inlet patches for globus sensation at our clinic. Symptoms were assessed by a visual analogue scale (VAS) in 31 of 49 patients. Follow-up endoscopy of the upper gastrointestinal tract was performed to confirm residual or relapsed cervical inlet patches. Results: After a median period of 27 months, APC was assessed as a successful therapy in 23 of 31 patients (74%). VAS scores decreased significantly from 7.6 to 4.0 in the long term. Twenty-two of 31 patients were willing to undergo follow-up endoscopy. Endoscopy revealed recurrent/residual gastric inlet patches after APC in 11 of 22 cases. These patients suffered from a significant relapse of symptoms in the postinterventional period (p < 0.001). Conclusion: This retrospective study indicates that APC of gastric inlet patches for the treatment of globus sensation might be a sufficient therapy option. Recurrences or residual heterotopic gastric mucosa are possible and seem to be associated with a relapse of symptoms. Therefore, endoscopic follow-up and retreatment might be necessary if globus sensation is not sufficiently eliminated. © 2013 S. Karger AG, Basel
Stichworte:
Globus sensation; Argon plasma coagulation; Inlet patches; Long-term outcome; Reflux
Zeitschriftentitel:
Digestion
Jahr:
2013
Band / Volume:
88
Heft / Issue:
3
Seitenangaben Beitrag:
165--171
Volltext / DOI:
doi:10.1159/000355274 Verlag / Institution:
S. Karger AG
Verlagsort:
Basel, Switzerland
Print-ISSN:
0012-2823
E-ISSN:
1421-9867
Hinweise:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
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