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Document type:
journal article 
Author(s):
Prager, Matthias; Durmus, Tahir; Büttner, Janine; Molnar, Tamas; de Jong, Dirk J; Drenth, Joost Ph; Baumgart, Daniel C; Sturm, Andreas; Farkas, Klaudia; Witt, Heiko; Büning, Carsten 
Title:
Myosin IXb variants and their pivotal role in maintaining the intestinal barrier: a study in Crohn's disease. 
Abstract:
Myosin IXb (MYO9B) is involved in the regulation of epithelial barrier function. We hypothesized that MYO9B variants are associated with increased intestinal permeability measured in patients with Crohn's disease (CD), where barrier dysfunction is crucially involved in disease development.We sequenced MYO9B and genotyped five MYO9B variants (rs1545620, rs1457092, rs2279003, rs2305764 and rs2279002) and correlated these data to measurement of intestinal permeability in German CD patients (n = 122...    »
 
Journal title abbreviation:
Scand J Gastroenterol 
Year:
2014 
Journal volume:
49 
Journal issue:
10 
Pages contribution:
1191-200 
Language:
eng 
Print-ISSN:
0036-5521 
TUM Institution:
Klinik für Ernährungsmedizin