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Document type:
journal article 
Author(s):
Nkosi, Pedro Junior; Targosz, Bianca-Sabrina; Labib, Karim; Sanchez-Diaz, Alberto 
Title:
Hof1 and Rvs167 have redundant roles in actomyosin ring function during cytokinesis in budding yeast. 
Abstract:
The Hof1 protein (Homologue of Fifteen) regulates formation of the primary septum during cytokinesis in the budding yeast Saccharomyces cerevisiae, whereas the orthologous Cdc15 protein in fission yeast regulates the actomyosin ring by using its F-BAR domain to recruit actin nucleators to the cleavage site. Here we show that budding yeast Hof1 also contributes to actin ring assembly in parallel with the Rvs167 protein. Simultaneous deletion of the HOF1 and RVS167 genes is lethal, and cells fail...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2013 
Journal volume:
Journal issue:
Pages contribution:
e57846 
Language:
eng 
TUM Institution:
III. Medizinische Klinik und Poliklinik