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Author(s):
Gu, Huiying; Wei, Xing; Chen, Shirley; Kurz, Alexander; Müller, Ulrich; Gasser, Thomas; Dodel, Richard C.; Farlow, Martin R.; Du, Yansheng 
Title:
Association of Clusterin Gene Polymorphisms with Late-Onset Alzheimer's Disease 
Abstract:
Background/Aims: Some studies have implicated the role of apolipoprotein J [clusterin (CLU), apoJ] in the pathogenesis of Alzheimer’s disease (AD). In this study, we investigated the polymorphisms rs11136000 and rs9331888 within CLU in late-onset sporadic AD (LOAD) patients and nondemented subjects. Methods: LOAD patients and control subjects were analyzed. Genotyping of rs11136000 and rs9331888 was performed using standard PCR following different restriction endonuclease digestion. Results: Alt...    »
 
Keywords:
Apolipoprotein J; Alzheimer’s disease, late-onset; Clusterin 
Journal title:
Dementia and Geriatric Cognitive Disorders 
Year:
2011 
Journal volume:
32 
Journal issue:
Pages contribution:
198--201 
Publisher:
S. Karger AG 
Publisher address:
Basel, Switzerland 
Print-ISSN:
1421-9824 
E-ISSN:
1421-9824 
Notes:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.