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Autor(en):
Junker, Kerstin; Weirich, Gregor; Moravek, Petr; Podhola, Miroslaw; Ilse, Bianka; Hartmann, Arndt; Schubert, Joerg 
Titel:
Familial and Sporadic Renal Oncocytomas -- A Comparative Molecular--Genetic Analysis 
Abstract:
Objectives: Genetic causes of sporadic and familial renal oncocytomas are not known. We analyzed these tumors genetically in order to detect tumor–specific chromosome alterations. Methods: DNA from 26 sporadic and 31 familial renal oncocytomas were screened by comparative genomic hybridization according to standard protocols including degenerate oligonucleotide–primed PCR. Results: Chromosome alterations were detected in 19/26 sporadic (73%) and in 4/31 familial renal oncocytomas (13%). Partial...    »
 
Stichworte:
Kidney cancer; Oncocytoma; Genetics; Comparative genomic hybridization; Familial oncocytoma 
Zeitschriftentitel:
European Urology 
Jahr:
2001 
Band / Volume:
40 
Heft / Issue:
Seitenangaben Beitrag:
330--336 
Verlag / Institution:
S. Karger AG 
Verlagsort:
Basel, Switzerland 
Print-ISSN:
1421-993X 
E-ISSN:
1421-993X 
Hinweise:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.