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Author(s):
Al-Chalabi, A.; Matevossian, E.; Preitextgreekbel, A.; Perren, A.; Yang, Z.; Schuster, T.; Schreiber, C.; Schimmel, P.; Nairz, E.; Yan, H.; Geiger, A.; Kreymann, B. 
Title:
A Model of Ischemic Isolated Acute Liver Failure in Pigs: Standardizing Monitoring and Treatment 
Abstract:
Background: Acute liver failure (ALF) models in pigs have been widely used for evaluating newly developed liver support systems. But hardly any guidelines are available for the surgical methods and the clinical management. Methods: The study validated several standard operating procedures describing in detail the surgical method and intensive care monitoring and treatment (control of potassium, glucose and bicarbonate levels, cardiovascular and intracranial pressure monitoring, etc.). ALF was in...    »
 
Keywords:
Acute liver failure; Portacaval shunt; Standardization 
Journal title:
European Surgical Research 
Year:
2010 
Journal volume:
45 
Journal issue:
Pages contribution:
86--97 
Publisher:
S. Karger AG 
Publisher address:
Basel, Switzerland 
Print-ISSN:
1421-9921 
E-ISSN:
1421-9921 
Notes:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.