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Autor(en):
Alessandrini, Francesca; Jakob, Thilo; Wolf, Alexander; Wolf, Eckhard; Balling, Rudolf; de Angelis, Martin Hrabe; Ring, Johannes; Behrendt, Heidrun 
Titel:
ENU Mouse Mutagenesis: Generation of Mouse Mutants with Aberrant Plasma IgE Levels 
Abstract:
Background: The ENU Mouse Mutagenesis Project aims at a large-scale, systematic production of mouse mutants using the alkylating agent ethyl-nitrosourea (ENU). Offspring of mutagenized mice are subjected to a multiparameter screen to detect alterations in various phenotypes with the ultimate goal of identifying novel genes relevant for the expression of the phenotype. Using this approach, we have analyzed plasma IgE concentrations to identify mouse mutants with aberrant plasma IgE levels. Method...    »
 
Stichworte:
IgE; Mutants; mouse; Mutagenesis 
Zeitschriftentitel:
International Archives of Allergy and Immunology 
Jahr:
2001 
Band / Volume:
124 
Heft / Issue:
1-3 
Seitenangaben Beitrag:
25--28 
Verlag / Institution:
S. Karger AG 
Verlagsort:
Basel, Switzerland 
Print-ISSN:
14230097 
E-ISSN:
1423-0097 
Hinweise:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.