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Author(s):
Alexopoulos, Panagiotis; Guo, Liang-Hao; Kratzer, Martina; Westerteicher, Christine; Kurz, Alexander; Perneczky, Robert 
Title:
Impact of SORL1 Single Nucleotide Polymorphisms on Alzheimer's Disease Cerebrospinal Fluid Markers 
Abstract:
Background: Recently, genetic variants of the neuronal sortilin-related receptor with A-type repeats (SORL1, also called LR11 or sorLA) have emerged as risk factors for the development of Alzheimer’s disease (AD). Methods: In this study, SORL1 gene polymorphisms, which have been shown to be related to AD, were analyzed for associations with cerebrospinal fluid (CSF) amyloid beta1–42 (Aβ1–42), phosphorylated tau181, and total tau levels in a non-Hispanic Caucasian sample, which encompassed 100 co...    »
 
Keywords:
Dementia; Mild cognitive impairment; Healthy aging; Amyloid cascade; Association 
Journal title:
Dementia and Geriatric Cognitive Disorders 
Year:
2011 
Journal volume:
32 
Journal issue:
Pages contribution:
164--170 
Fulltext / DOI:
Publisher:
S. Karger AG 
Publisher address:
Basel, Switzerland 
Print-ISSN:
1421-9824 
E-ISSN:
1421-9824 
Notes:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.