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Dokumenttyp:
Zeitschriftenaufsatz 
Autor(en):
Depboylu, Candan; Lohmüller, Frank; Gocke, Petra; Du, Yansheng; Zimmer, Reinhilde; Gasser, Thomas; Klockgether, Thomas; Dodel, Richard C. 
Titel:
An Interleukin-6 Promoter Variant Is Not Associated with an Increased Risk for Alzheimer's Disease 
Abstract:
Recent studies have implicated interleukin-6 (IL-6) in the pathogenesis of Alzheimer’s disease (AD). Neuro-inflammatory processes surrounding the amyloid plaques contribute to the progression of AD-related neurodegeneration. IL-6 is a multifunctional inflammatory cytokine which possibly acts as a mediator in the local immune response in the brain of AD patients. In this study we investigated whether the risk of developing AD is altered in carriers of the C allele of a G/C polymorphism at positio...    »
 
Stichworte:
Neurodegeneration; Pro-inflammatory cytokines; Cytokine; Polymorphism 
Zeitschriftentitel:
Dementia and Geriatric Cognitive Disorders 
Jahr:
2004 
Band / Volume:
17 
Heft / Issue:
Seitenangaben Beitrag:
170--173 
Verlag / Institution:
S. Karger AG 
Verlagsort:
Basel, Switzerland 
Print-ISSN:
14219824 
E-ISSN:
1421-9824 
Hinweise:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.