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Dokumenttyp:
Zeitschriftenaufsatz 
Autor(en):
Buters, Jeroen T.M.; Kasche, Anna; Weichenmeier, Ingrid; Schober, Wolfgang; Klaus, Sabrina; Traidl-Hoffmann, Claudia; Menzel, Annette; Huss-Marp, Johannes; Krämer, Ursula; Behrendt, Heidrun 
Titel:
Year-to-Year Variation in Release of Bet v 1 Allergen from Birch Pollen: Evidence for Geographical Differences between West and South Germany 
Abstract:
Background: The release of the aeroallergen Bet v 1 from pollen is a major determinant in the etiology of allergic airway disease due to birch pollen. Objective: We determined the release of the major birch pollen allergen Bet v 1 from pollen of birch trees growing in 2 different geographic regions in Germany for 2 consecutive years. Methods: Catkins were collected during pollination in 2002 and 2003 from 82 healthy trees in South (Munich) and West Germany (North Rhine-Westphalia). The release of Bet v 1 from pollen samples was determined by a Bet v 1-specific ELISA. Results: Pollen from South Germany released about 3 times more Bet v 1 than those from West Germany in both 2002 and 2003 (p = 0.034 and p = 0.007, respectively). This was independent of the number of pollen during the pollen flight season. In 2003, the release of Bet v 1 from pollen was more than 5 times higher than in 2002 in both regions (South Germany 6.1 times, p < 0.001; West Germany 5.4 times, p = 0.003). Conclusions: Despite large individual differences, there seem to be regional and year-to-year variations in Bet v 1 release from birch pollen. Therefore, the combination of pollen count and release of Bet v 1 from this pollen must be assessed to estimate Bet v 1 exposure reliably. 
Stichworte:
Birch; Pollen; Seasonal; Bet v 1; Regional 
Zeitschriftentitel:
International Archives of Allergy and Immunology 
Jahr:
2008 
Band / Volume:
145 
Heft / Issue:
Seitenangaben Beitrag:
122--130 
Verlag / Institution:
S. Karger AG 
Verlagsort:
Basel, Switzerland 
Print-ISSN:
1423-0097 
E-ISSN:
1423-0097 
Hinweise:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.