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Autor(en):
Schmid, Hans-Peter; Gregorin, Joel; Altwein, Jens E. 
Titel:
Growth Hormone Inhibitors in Prostate Cancer: A Systematic Analysis 
Abstract:
Objective: Despite initial therapeutic success through androgen ablation in patients with advanced prostate cancer, the vast majority progress to androgen independence. Somatostatin (SST) analogs are a viable therapeutic modality before resorting to chemotherapy or immunotherapy. Their mechanism of action is related to a reduction in the IGF-1 (survival factor, reaction on neuroendocrine cells) appearing incrementally after long-term androgen deprivation and a possible suppression of GnRH recept...    »
 
Stichworte:
Prostate cancer; Growth hormone inhibitors; Somatostatins 
Zeitschriftentitel:
Urologia Internationalis 
Jahr:
2008 
Band / Volume:
81 
Heft / Issue:
Seitenangaben Beitrag:
17--22 
Verlag / Institution:
S. Karger AG 
Verlagsort:
Basel, Switzerland 
Print-ISSN:
1423-0399 
E-ISSN:
1423-0399 
Hinweise:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.