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Document type:
journal article 
Author(s):
Lemke, Dieter; Weiler, Markus; Blaes, Jonas; Wiestler, Benedikt; Jestaedt, Leonie; Klein, Ann-Catherine; Löw, Sarah; Eisele, Günter; Radlwimmer, Bernhard; Capper, David; Schmieder, Kirsten; Mittelbronn, Michel; Combs, Stephanie E; Bendszus, Martin; Weller, Michael; Platten, Michael; Wick, Wolfgang 
Title:
Primary glioblastoma cultures: can profiling of stem cell markers predict radiotherapy sensitivity? 
Abstract:
Human glioblastomas may be hierarchically organized. Within this hierarchy, glioblastoma-initiating cells have been proposed to be more resistant to radiochemotherapy and responsible for recurrence. Here, established stem cell markers and stem cell attributed characteristics such as self-renewal capacity and tumorigenicity have been profiled in primary glioblastoma cultures to predict radiosensitivity. Furthermore, the sensitivity to radiotherapy of different subpopulations within a single prima...    »
 
Journal title abbreviation:
J Neurochem 
Year:
2014 
Journal volume:
131 
Journal issue:
Pages contribution:
251-64 
Language:
eng 
Print-ISSN:
0022-3042 
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie