Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Sassi, Yassine; Hulot, Jean-Sébastien 
Titel:
Pulmonary Hypertension: Novel Pathways and Emerging Therapies Inhibitors of cGMP and cAMP Metabolism. 
Abstract:
Cyclic nucleotides (e.g., cAMP and cGMP) are ubiquitous second messengers that affect multiple cell functions including vascular tone and vascular cell proliferation. After production, different processes can regulate the concentration of cyclic nucleotides. Cyclic nucleotides' degradation by phosphodiesterase (PDE) enzymes has well-known roles in regulating cyclic nucleotides concentrations. Recently, recognition of ATP-binding cassette (ABC) transporter contribution to both local and global re...    »
 
Zeitschriftentitel:
Handb Exp Pharmacol 
Jahr:
2013 
Band / Volume:
218 
Seitenangaben Beitrag:
513-29 
Sprache:
eng 
Print-ISSN:
0171-2004 
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie