User: Guest  Login
Document type:
journal article 
Author(s):
Methner, Carmen; Lukowski, Robert; Grube, Karina; Loga, Florian; Smith, Robin A J; Murphy, Michael P; Hofmann, Franz; Krieg, Thomas 
Title:
Protection through postconditioning or a mitochondria-targeted S-nitrosothiol is unaffected by cardiomyocyte-selective ablation of protein kinase G. 
Abstract:
Protein kinase G type I (PKGI) plays a critical role in survival signaling of pre- and postconditioning downstream of cardiac cGMP. However, it is unclear whether PKGI exerts its protective effects in the cardiomyocyte or if other cardiac cell types are involved, and whether nitric oxide (NO) metabolism can target cardiomyocyte mitochondria independently of cGMP/PKGI. We tested whether protection against reperfusion injury by ischemic postconditioning (IPost), soluble guanylyl cyclase (sGC) acti...    »
 
Journal title abbreviation:
Basic Res Cardiol 
Year:
2013 
Journal volume:
108 
Journal issue:
Pages contribution:
337 
Language:
eng 
Print-ISSN:
0300-8428 
TUM Institution:
Institut für Pharmakologie und Toxikologie