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Document type:
journal article 
Author(s):
Dukart, J; Perneczky, R; Förster, S; Barthel, H; Diehl-Schmid, J; Draganski, B; Obrig, H; Santarnecchi, E; Drzezga, A; Fellgiebel, A; Frackowiak, R; Kurz, A; Müller, K; Sabri, O; Schroeter, ML; Yakushev, I 
Title:
Reference cluster normalization improves detection of frontotemporal lobar degeneration by means of FDG-PET. 
Abstract:
Positron emission tomography with [18F] fluorodeoxyglucose (FDG-PET) plays a well-established role in assisting early detection of frontotemporal lobar degeneration (FTLD). Here, we examined the impact of intensity normalization to different reference areas on accuracy of FDG-PET to discriminate between patients with mild FTLD and healthy elderly subjects. FDG-PET was conducted at two centers using different acquisition protocols: 41 FTLD patients and 42 controls were studied at center 1, 11 FTL...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2013 
Journal volume:
Journal issue:
Pages contribution:
e55415 
Language:
eng 
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie; Nuklearmedizinische Klinik und Poliklinik