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Document type:
journal article 
Author(s):
Sorg, C; Manoliu, A; Neufang, S; Myers, N; Peters, H; Schwerthöffer, D; Scherr, M; Mühlau, M; Zimmer, C; Drzezga, A; Förstl, H; Bäuml, J; Eichele, T; Wohlschläger, AM; Riedl, V 
Title:
Increased intrinsic brain activity in the striatum reflects symptom dimensions in schizophrenia. 
Abstract:
Striatal dysfunction is thought to be a fundamental element in schizophrenia. Striatal dopamine dysfunction impacts on reward processing and learning and is present even at rest. Here, we addressed the question whether and how spontaneous neuronal activity in the striatum is altered in schizophrenia. We therefore assessed intrinsic striatal activity and its relation with disorder states and symptom dimensions in patients with schizophrenia. We performed resting-state functional (rs-fMRI) and str...    »
 
Journal title abbreviation:
Schizophr Bull 
Year:
2013 
Journal volume:
39 
Journal issue:
Pages contribution:
387-95 
Language:
eng 
Print-ISSN:
0586-7614 
TUM Institution:
Abteilung für Neuroradiologie; Klinik und Poliklinik für Psychiatrie und Psychotherapie; Neurologische Klinik und Poliklinik; Nuklearmedizinische Klinik und Poliklinik