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Dokumenttyp:
journal article 
Autor(en):
Kim, Mia; Grimmig, Tanja; Grimm, Martin; Lazariotou, Maria; Meier, Eva; Rosenwald, Andreas; Tsaur, Igor; Blaheta, Roman; Heemann, Uwe; Germer, Christoph-Thomas; Waaga-Gasser, Ana Maria; Gasser, Martin 
Titel:
Expression of Foxp3 in colorectal cancer but not in Treg cells correlates with disease progression in patients with colorectal cancer. 
Abstract:
Regulatory T cells (Treg) expressing the transcription factor forkhead-box protein P3 (Foxp3) have been identified to counteract anti-tumor immune responses during tumor progression. Besides, Foxp3 presentation by cancer cells itself may also allow them to evade from effector T-cell responses, resulting in a survival benefit of the tumor. For colorectal cancer (CRC) the clinical relevance of Foxp3 has not been evaluated in detail. Therefore the aim of this study was to study its impact in colore...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2013 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
e53630 
Sprache:
eng 
TUM Einrichtung:
Abteilung für Nephrologie