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Dokumenttyp:
journal article 
Autor(en):
Achenbach, P; Hummel, M; Thümer, L; Boerschmann, H; Höfelmann, D; Ziegler, A G 
Titel:
Characteristics of rapid vs slow progression to type 1 diabetes in multiple islet autoantibody-positive children. 
Abstract:
Islet autoantibody-positive children progress to type 1 diabetes at variable rates. In our study, we asked whether characteristic autoantibody and/or gene profiles could be defined for phenotypes showing extreme progression.Autoantibodies to insulin (IAA), GAD (GADA), insulinoma-associated antigen-2 (IA-2A) and zinc transporter 8 (ZnT8A) were measured in follow-up sera, and genotyping for type 1 diabetes susceptibility genes (HLA-DR/HLA-DQ, INS variable number of tandem repeats [VNTR] and single...    »
 
Zeitschriftentitel:
Diabetologia 
Jahr:
2013 
Band / Volume:
56 
Heft / Issue:
Seitenangaben Beitrag:
1615-22 
Sprache:
eng 
Print-ISSN:
0012-186X 
TUM Einrichtung:
Kinderklinik und Poliklinik