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Dokumenttyp:
journal article 
Autor(en):
Fleury, Lauren M; Wilson, Erin E; Vogt, Monika; Fan, Tiffany J; Oliver, Allen G; Ashfeld, Brandon L 
Titel:
Amine-free approach toward N-toluenesulfonyl amidine construction: a phosphite-mediated Beckmann-like coupling of oximes and p-toluenesulfonyl azide. 
Abstract:
Atom hopping: A chlorophosphite-mediated Beckmann ligation of oximes and p-toluenesulfonyl azide gives access to N-sulfonyl phosphoramidines in good to excellent yields. The reaction proceeds under exceptionally mild conditions and constitutes a bioorthogonal approach toward amidines by avoiding the use of amines and transition-metal catalysts. dmp-ol=3,3-dimethylpropanediol. 
Zeitschriftentitel:
Angew Chem Int Ed Engl 
Jahr:
2013 
Band / Volume:
52 
Heft / Issue:
44 
Seitenangaben Beitrag:
11589-93 
Sprache:
eng 
Print-ISSN:
0570-0833 
TUM Einrichtung:
Klinik für Kinderkardiologie und angeborene Herzfehler