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Document type:
journal article 
Author(s):
Pfarr, Nicole, N; Fischer, Christine, C; Ehlken, Nicola, N; Becker-Grünig, Tabea, T; López-González, Vanesa, V; Gorenflo, Matthias, M; Hager, Alfred, A; Hinderhofer, Katrin, K; Miera, Oliver, O; Nagel, Christian, C; Schranz, Dietmar, D; Grünig, Ekkehard, E 
Title:
Hemodynamic and genetic analysis in children with idiopathic, heritable, and congenital heart disease associated pulmonary arterial hypertension. 
Abstract:
Aim of this prospective study was to compare clinical and genetic findings in children with idiopathic or heritable pulmonary arterial hypertension (I/HPAH) with children affected with congenital heart defects associated PAH (CHD-APAH).Prospectively included were 40 consecutive children with invasively diagnosed I/HPAH or CHD-APAH and 117 relatives. Assessment of family members, pedigree analysis and systematic screening for mutations in TGFß genes were performed.Five mutations in the bone morph...    »
 
Journal title abbreviation:
Respir Res 
Year:
2013 
Journal volume:
14 
Pages contribution:
Language:
eng 
Print-ISSN:
1465-9921 
TUM Institution:
Klinik für Kinderkardiologie und angeborene Herzfehler