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Document type:
journal article 
Author(s):
Bergmann, Frank; Aulmann, Sebastian; Sipos, Bence; Kloor, Matthias; von Heydebreck, Anja; Schweipert, Johannes; Harjung, Andreas; Mayer, Philipp; Hartwig, Werner; Moldenhauer, Gerhard; Capper, David; Dyckhoff, Gerhard; Freier, Kolja; Herpel, Esther; Schleider, Anja; Schirmacher, Peter; Mechtersheimer, Gunhild; Klöppel, Günter; Bläker, Hendrik 
Title:
Acinar cell carcinomas of the pancreas: a molecular analysis in a series of 57 cases. 
Abstract:
Pancreatic acinar cell carcinomas (PACs) are rare but are distinct aggressive neoplasms that phenotypically differ from pancreatic ductal adenocarcinomas (PDACs) and pancreatic neuroendocrine neoplasms (PNENs). Despite recent work on the genetic changes of PACs, their molecular pathogenesis is still poorly understood. In this study, we focus on a comparative genomic hybridization analysis. Based on frequent chromosomal imbalances, the involvement of DCC and c-MYC in the pathogenesis of PACs is f...    »
 
Journal title abbreviation:
Virchows Arch 
Year:
2014 
Journal volume:
465 
Journal issue:
Pages contribution:
661-72 
Language:
eng 
Print-ISSN:
0945-6317 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie