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Dokumenttyp:
journal article 
Autor(en):
Li, Z; Herrmann, K; Pirsig, S; Philipp-Abbrederis, K; Henninger, M; Aichler, M; Feuchtinger, A; Walch, A; Beer, AJ; Ringshausen, I; Pomykala, KL; Scheidhauer, K; Schwaiger, M; Keller, U; Buck, AK 
Titel:
Molecular imaging for early prediction of response to Sorafenib treatment in sarcoma. 
Abstract:
The role of [(18)F]fluorodeoxyglucose ([(18)F]FDG) PET in staging of sarcoma is well established. The aim of this preclinical study was to compare [(18)F]fluorothymidine ([(18)F]FLT) PET to [(18)F]FDG PET regarding early metabolic changes of sarcoma in the course of targeted cancer therapy. SCID mice bearing sarcoma A673 xenotransplants were used for investigation of tumor response after treatment with the multikinase inhibitor Sorafenib. [(18)F]FLT and/or [(18)F]FDG-PET were performed prior to...    »
 
Zeitschriftentitel:
Am J Nucl Med Mol Imaging 
Jahr:
2013 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
70-9 
Sprache:
eng 
TUM Einrichtung:
Nuklearmedizinische Klinik und Poliklinik; III. Medizinische Klinik und Poliklinik