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Dokumenttyp:
journal article 
Autor(en):
Manthey, HD; Cochain, C; Barnsteiner, S; Karshovska, E; Pelisek, J; Koch, M; Chaudhari, SM; Busch, M; Eckstein, HH; Weber, C; Koenen, RR; Zernecke, A 
Titel:
CCR6 selectively promotes monocyte mediated inflammation and atherogenesis in mice. 
Abstract:
The chemokine receptor CCR6 is expressed by various cell subsets implicated in atherogenesis, such as monocytes, Th17 and regulatory T cells. In order to further define the role of CCR6 in atherosclerosis, CCR6-deficient (Ccr6-/-) mice were crossed with low-density lipoprotein receptor-deficient (Ldlr-/-) mice to generate atherosclerosis-prone mice deficient in CCR6. Compared to Ldlr-/- controls, atherosclerotic burden in the aortic sinus and aorta were reduced in Ccr6-/-Ldlr-/- mice fed a high...    »
 
Zeitschriftentitel:
Thromb Haemost 
Jahr:
2013 
Band / Volume:
110 
Heft / Issue:
Seitenangaben Beitrag:
1267-77 
Sprache:
eng 
Print-ISSN:
0340-6245 
TUM Einrichtung:
Klinik für Gefäßchirurgie