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Dokumenttyp:
journal article 
Autor(en):
Zirbs, M; Pürner, C; Buters, JT; Effner, R; Weidinger, S; Ring, J; Eberlein, B 
Titel:
GSTM1, GSTT1 and GSTP1 gene polymorphism in polymorphous light eruption. 
Abstract:
Polymorphous light eruption (PLE) is the most common chronic and idiopathic photodermatosis. PLE is assumed to represent an immunological hypersensitivity reaction to a radiation-induced cutaneous antigen involving reactive oxygen species (ROS) on the basis of a genetic predisposition. Among others, cellular protection against ROS is provided by glutathione S-transferases (GSTs). Different variants of the GST enzymes may influence the activity and efficiency of detoxification and biotransformati...    »
 
Zeitschriftentitel:
J Eur Acad Dermatol Venereol 
Jahr:
2013 
Band / Volume:
27 
Heft / Issue:
Seitenangaben Beitrag:
157-62 
Sprache:
eng 
Print-ISSN:
0926-9959 
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie; Institut für Molekulare Allergologie und Umweltforschung