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Dokumenttyp:
journal article 
Autor(en):
Erkan, Mert 
Titel:
Understanding the stroma of pancreatic cancer: co-evolution of the microenvironment with epithelial carcinogenesis. 
Abstract:
Pancreatic ductal adenocarcinoma (PDAC) is a notoriously therapy-resistant desmoplastic tumour. Antifibrotic therapy is shown to increase drug delivery in the preclinical setting. However, this approach can be a double-edged sword: first, PDAC is not uniform and some types of (dormant) stroma may in fact be protective; second, conventional chemotherapeutics are not powerful enough to eradicate all cancer cells in the tumour, therefore breaking down the stromal wall non-selectively may also lead...    »
 
Zeitschriftentitel:
J Pathol 
Jahr:
2013 
Band / Volume:
231 
Heft / Issue:
Seitenangaben Beitrag:
4-7 
Sprache:
eng 
Print-ISSN:
0022-3417 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik