Übersetzte Kurzfassung:
In a randomized double-blind trial, the efficacy and safety of cholinesterase inhibitor donepezil in preventing postoperative delirium was investigated. In comparison with placebo, donepezil did not reduce the incidence or severity of postoperative delirium in patients older than 70 years undergoing elective endoprosthetic surgery. No severe side effects were observed.