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Autor(en):
Winkler, C.; Krumsiek, J.; Lempainen, J.; Achenbach, P.; Grallert, H.; Giannopoulou, E.; Bunk, M.; Theis, F. J.; Bonifacio, E.; Ziegler, A. G. 
Titel:
A strategy for combining minor genetic susceptibility genes to improve prediction of disease in type 1 diabetes 
Abstract:
Genome-wide association studies have identified gene regions associated with type 1 diabetes. The aim of this study was to determine how the combined allele frequency of multiple susceptibility genes can stratify islet autoimmunity and/or type 1 diabetes risk. Children of parents with type 1 diabetes and prospectively followed from birth for the development of islet autoantibodies and diabetes were genotyped for single-nucleotide polymorphisms at 12 type 1 diabetes susceptibility genes (ERBB3, P...    »
 
Stichworte:
type 1 diabetes type 1 diabetes susceptibility genes islet autoimmunity 
Zeitschriftentitel:
Genes Immun. 
Jahr:
2012 
Band / Volume:
13 
Heft / Issue:
Seitenangaben Beitrag:
549-555