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Author(s):
Meyer-Bäse, A.; Theis, F. J.; Emmett, M. R. 
Title:
Robust stability analysis and design under consideration of multiple feedback loops of the tryptophan regulatory network of Escherichia coli 
Abstract:
The tryptophan system present in Escherichia coli represents an important regulatory unit described by multiple feedback loops. The role of these feedback loops is crucial for the analysis of the dynamical behavior of the tryptophan synthesis. We analyze the robust stability of this system which models the dynamics of both fast state, such as transcription and synthesis of free operator, and slow state, such as translation and tryptophan synthesis under consideration of nonlinear uncertainties....    »
 
Keywords:
tryptophan system robust stability biological regulators singulary perturbed system, E. coli Multiple feedback loops Stability analysis Tryptophan regulatory network 
Journal title:
Adv. Exp. Med. Biol. 
Year:
2010 
Journal volume:
680 
Pages contribution:
189-197