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Autor(en):
Marr, C.; Theis, F. J.; Liebovitch, L. S.; Hütt, M. T. 
Titel:
Patterns of subnet usage reveal distinct scales of regulation in the transcriptional regulatory network of Escherichia coli 
Abstract:
The set of regulatory interactions between genes, mediated by transcription factors, forms a species' transcriptional regulatory network (TRN). By comparing this network with measured gene expression data, one can identify functional properties of the TRN and gain general insight into transcriptional control. We define the subnet of a node as the subgraph consisting of all nodes topologically downstream of the node, including itself. Using a large set of microarray expression data of the bacter...    »
 
Stichworte:
Genomic analysis Expression data Profiles Motifs 
Zeitschriftentitel:
PLoS Comput. Biol. 
Jahr:
2010 
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