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Autor(en):
Bardehle, S.; Krüger, M.; Buggenthin, F.; Schwausch, J.; Ninkovic, J.; Clevers, H.; Snippert, H. J.; Theis, F. J.; Meyer-Luehmann, M.; Bechmann, I.; Dimou, L.; Götz, M. 
Titel:
Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation 
Abstract:
Astrocytes are thought to have important roles after brain injury, but their behavior has largely been inferred from postmortem analysis. To examine the mechanisms that recruit astrocytes to sites of injury, we used in vivo two-photon laser-scanning microscopy to follow the response of GFP-labeled astrocytes in the adult mouse cerebral cortex over several weeks after acute injury. Live imaging revealed a marked heterogeneity in the reaction of individual astrocytes, with one subset retaining the...    »
 
Zeitschriftentitel:
Nat. Neurosci. 
Jahr:
2013 
Band / Volume:
16 
Heft / Issue:
Seitenangaben Beitrag:
580-586