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Dokumenttyp:
journal article 
Autor(en):
Krepstakies, M; Lucifora, J; Nagel, CH; Zeisel, MB; Holstermann, B; Hohenberg, H; Kowalski, I; Gutsmann, T; Baumert, TF; Brandenburg, K; Hauber, J; Protzer, U 
Titel:
A new class of synthetic peptide inhibitors blocks attachment and entry of human pathogenic viruses. 
Abstract:
Many enveloped viruses, including herpes viruses, hepatitis B virus (HBV), and hepatitis C virus (HCV), and human immunodeficiency virus (HIV), are among the most important human pathogens and are often responsible for coinfections involving>=2 types of viruses. However, therapies that are effective against multiple virus classes are rare. Here we present a new class of synthetic anti-lipopolysaccharide peptides (SALPs) that bind to heparan sulfate moieties on the cell surface and inhibit infect...    »
 
Zeitschriftentitel:
J Infect Dis 
Jahr:
2012 
Band / Volume:
205 
Heft / Issue:
11 
Seitenangaben Beitrag:
1654-64 
Sprache:
eng 
Print-ISSN:
0022-1899 
TUM Einrichtung:
r Virologie