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Dokumenttyp:
journal article 
Autor(en):
Vaupel, P; Mayer, A 
Titel:
Availability, not respiratory capacity governs oxygen consumption of solid tumors. 
Abstract:
Contrary to conventional belief, the mitochondria of most cancer cells usually function normally, i.e., their respiratory capacity is not fundamentally impaired as compared to normal cells. Strong evidence against the misconception of mitochondrial dysfunction is provided by in vivo data clearly showing that O(2) availability is the major determinant of the O(2) consumption rate of cancer cells, independent of the means for increasing availability (e.g., by increasing blood flow or by elevating...    »
 
Zeitschriftentitel:
Int J Biochem Cell Biol 
Jahr:
2012 
Band / Volume:
44 
Heft / Issue:
Seitenangaben Beitrag:
1477-81 
Sprache:
eng 
Print-ISSN:
1357-2725 
TUM Einrichtung:
r Strahlentherapie und Radiologische Onkologie