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Document type:
journal article 
Author(s):
Fox, B; Schantz, JT; Haigh, R; Wood, ME; Moore, PK; Viner, N; Spencer, JP; Winyard, PG; Whiteman, M 
Title:
Inducible hydrogen sulfide synthesis in chondrocytes and mesenchymal progenitor cells: is H(2) S a novel cytoprotective mediator in the inflamed joint? 
Abstract:
Hydrogen sulfide (H(2) S) has recently been proposed as an endogenous mediator of inflammation and is present in human synovial fluid. This study determined whether primary human articular chondrocytes (HACs) and mesenchymal progenitor cells (MPCs) could synthesize H(2) S in response to pro-inflammatory cytokines relevant to human arthropathies, and to determine the cellular responses to endogenous and pharmacological H(2) S. HACs and MPCs were exposed to IL-1?, IL-6, TNF-? and lipopolysaccharid...    »
 
Journal title abbreviation:
J Cell Mol Med 
Year:
2012 
Journal volume:
16 
Journal issue:
Pages contribution:
896-910 
Language:
eng 
Print-ISSN:
1582-1838 
TUM Institution:
Klinik und Poliklinik für Plastische Chirurgie und Handchirurgie