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Document type:
journal article 
Author(s):
Jentzsch, C; Leierseder, S; Loyer, X; Flohrschütz, I; Sassi, Y; Hartmann, D; Thum, T; Laggerbauer, B; Engelhardt, S 
Title:
A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes. 
Abstract:
MicroRNAs (miRNAs) are small non-coding RNAs that control expression of complementary target mRNAs. A growing number of miRNAs has been implicated in the pathogenesis of cardiac diseases, mostly based not on functional data, but on the observation that they are dysregulated in diseased myocardium. Consequently, our knowledge regarding a potential cardiac role of the majority of miRNAs is limited. Here, we report the development of an assay format that allows the simultaneous analysis of several...    »
 
Journal title abbreviation:
J Mol Cell Cardiol 
Year:
2012 
Journal volume:
52 
Journal issue:
Pages contribution:
13-20 
Language:
eng 
Print-ISSN:
0022-2828 
TUM Institution:
Institut für Pharmakologie und Toxikologie