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Dokumenttyp:
journal article 
Autor(en):
Turner, JE; Krebs, C; Tittel, AP; Paust, HJ; Meyer-Schwesinger, C; Bennstein, SB; Steinmetz, OM; Prinz, I; Magnus, T; Korn, T; Stahl, RA; Kurts, C; Panzer, U 
Titel:
IL-17A production by renal ?? T cells promotes kidney injury in crescentic GN. 
Abstract:
The Th17 immune response appears to contribute to the pathogenesis of human and experimental crescentic GN, but the cell types that produce IL-17A in the kidney, the mechanisms involved in its induction, and the IL-17A-mediated effector functions that promote renal tissue injury are incompletely understood. Here, using a murine model of crescentic GN, we found that CD4(+) T cells, ?? T cells, and a population of CD3(+)CD4(-)CD8(-)??T cell receptor(-)NK1.1(-) T cells all produce IL-17A in the kid...    »
 
Zeitschriftentitel:
J Am Soc Nephrol 
Jahr:
2012 
Band / Volume:
23 
Heft / Issue:
Seitenangaben Beitrag:
1486-95 
Sprache:
eng 
Print-ISSN:
1046-6673 
TUM Einrichtung:
Neurologische Klinik und Poliklinik