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Dokumenttyp:
journal article 
Autor(en):
Wegner, F; Kraft, R; Busse, K; Härtig, W; Ahrens, J; Leffler, A; Dengler, R; Schwarz, J 
Titel:
Differentiated human midbrain-derived neural progenitor cells express excitatory strychnine-sensitive glycine receptors containing ?2? subunits. 
Abstract:
Human fetal midbrain-derived neural progenitor cells (NPCs) may deliver a tissue source for drug screening and regenerative cell therapy to treat Parkinson's disease. While glutamate and GABA(A) receptors play an important role in neurogenesis, the involvement of glycine receptors during human neurogenesis and dopaminergic differentiation as well as their molecular and functional characteristics in NPCs are largely unknown.Here we investigated NPCs in respect to their glycine receptor function a...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2012 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
e36946 
Sprache:
eng 
TUM Einrichtung:
Neurologische Klinik und Poliklinik