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Dokumenttyp:
journal article 
Autor(en):
Gertz, K; Kronenberg, G; Kälin, RE; Baldinger, T; Werner, C; Balkaya, M; Eom, GD; Hellmann-Regen, J; Kröber, J; Miller, KR; Lindauer, U; Laufs, U; Dirnagl, U; Heppner, FL; Endres, M 
Titel:
Essential role of interleukin-6 in post-stroke angiogenesis. 
Abstract:
Ambivalent effects of interleukin-6 on the pathogenesis of ischaemic stroke have been reported. However, to date, the long-term actions of interleukin-6 after stroke have not been investigated. Here, we subjected interleukin-6 knockout (IL-6(-/-)) and wild-type control mice to mild brain ischaemia by 30-min filamentous middle cerebral artery occlusion/reperfusion. While ischaemic tissue damage was comparable at early time points, IL-6(-/-) mice showed significantly increased chronic lesion volum...    »
 
Zeitschriftentitel:
Brain 
Jahr:
2012 
Band / Volume:
135 
Heft / Issue:
Pt 6 
Seitenangaben Beitrag:
1964-80 
Sprache:
eng 
Print-ISSN:
0006-8950 
TUM Einrichtung:
Neurochirurgische Klinik und Poliklinik