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Document type:
journal article 
Author(s):
EVOLVE Trial Investigators; Chertow, GM; Block, GA; Correa-Rotter, R; Drüeke, TB; Floege, J; Goodman, WG; Herzog, CA; Kubo, Y; London, GM; Mahaffey, KW; Mix, TC; Moe, SM; Trotman, ML; Wheeler, DC; Parfrey, PS; Chertow, G; Parfrey, P; Block, G; Correa-Rotter, R; Drüeke, T; Floege, J; Goodman, W; Herzog, C; London, G; Mahaffey, K; Moe, S; Wheeler, D; Hennekens, C; Baigent, C; Brown, W; O'Brien, P; Anderson, S; Hoel, J; Mahaffey, K; Szczech, L; Patel, U; Wampole, J; Pun, P; Felker, M; Inrig, J; Sha...    »
 
Title:
Effect of cinacalcet on cardiovascular disease in patients undergoing dialysis. 
Abstract:
Disorders of mineral metabolism, including secondary hyperparathyroidism, are thought to contribute to extraskeletal (including vascular) calcification among patients with chronic kidney disease. It has been hypothesized that treatment with the calcimimetic agent cinacalcet might reduce the risk of death or nonfatal cardiovascular events in such patients.In this clinical trial, we randomly assigned 3883 patients with moderate-to-severe secondary hyperparathyroidism (median level of intact parath...    »
 
Journal title abbreviation:
N Engl J Med 
Year:
2012 
Journal volume:
367 
Journal issue:
26 
Pages contribution:
2482-94 
Language:
eng 
Print-ISSN:
0028-4793 
TUM Institution:
Abteilung für Nephrologie